Cosmetic Injectables

Botulinum toxin

  • The most popular cosmetic injection, is used to correct wrinkles and lines that develop over time as you use the muscles in your face (among many other purposes). The results are temporary, but people continuously return for more.

  • FDA-approved neurotoxins: Botox, Dysport, Jeuveau, and Xeomin.


WHAT’S THE DIFFERENCE BETWEEN BOTOX, DYSPORT, XEOMIN AND JEUVEAU?

BOTOX, Dysport, Xeomin and Jeuveau injections have become increasingly popular in recent years. Consisting of a neuromodulator, they are able to relax muscles by temporarily blocking neurological signals. As a result, all four types of injections are effective at reducing the appearance of wrinkles and fine lines. With that said, there are subtle nuances between BOTOX, Dysport, Xeomin and Jeuveau. Before scheduling an appointment for any of these injections, you should familiarize yourself with their unique characteristics.

WHAT IS BOTOX?

Developed and marketed by Allergan, BOTOX is an injection consisting of a specific formulation of botulinum toxin (BTX) known as onabotulinumtoxinA. It’s injected directly into muscle tissue for the purpose of blocking neurological signals to the respective tissue. Our muscles rely on neurological signals to contract. When you flex a muscle, your brain is telling that muscle to contract. If a muscle remains in a contracted state, however, it may cause discomfort as well as the formation of wrinkles or fine lines. BOTOX injections are designed to relax contracted muscle tissue such as this by blocking neurological signals.

WHAT IS DYSPORT?

Like BOTOX, Dysport is an injection containing BTX that’s designed to block neurological signals to the targeted muscle tissue. With that said, Dysport uses a different formulation of BTX than BOTOX. While BOTOX uses onabotulinumtoxinA, Dysport uses abobotulinumtoxinA. It still consists of the same basic neuromodulator that temporarily blocks neurological signals to the muscle or muscles in which it’s injected. Furthermore, the Dysport injections are administered in the same way as BOTOX injections, with each session lasting about 10 minutes. But Dysport uses a different formulation of BTX than its BOTOX counterpart, resulting in a few subtle differences.

WHAT IS XEOMIN?

As you may have guessed, Xeomin is an injection featuring yet another formulation of BTX. Produced by the German pharmaceutical company Merz Pharma GmbH & Co., it uses incobotulinumtoxinA. Xeomin is often used for the same purposes as both BOTOX and Dysport, including but not limited to the reduction of wrinkles and fine lines. Once injected into muscle tissue, Xeomin’s incobotulinumtoxinA temporarily blocks neurological signals to the respective tissue, thereby forcing the muscle or muscles to relax.

Since Xeomin isn’t formulated with any complexing proteins, patients who show signs of BOTOX resistance may experience better results.

WHAT IS JEUVEAU?

Also known as NEWTOX, Jeuveau is an injection that uses botulinum toxin type A. It works like other BTX injections by temporarily blocking neurological signals to muscles. While relatively new — first approved by the FDA in 2019 — Jeuveau has become a popular alternative to BOTOX because of its low cost. The true cost of an injection varies depending on many factors, but Jeuveau injections typically cost less than BOTOX injections. Evolus, the company that makes Jeuveau, was able to achieve a lower price by focusing specifically on cosmetic applications for its product. While BOTOX is approved for both cosmetic and medical applications, Jeuveau is only approved for cosmetic applications, including the treatment of wrinkles and frown lines.

How do neurotoxins work?

Neuromodulators (used interchangeably with “neurotoxins”) work by temporarily paralyzing the facial muscles responsible for causing the lines and wrinkles visible when your face is at rest. As a result, their appearance is greatly reduced, providing a more youthful and refreshed appearance.

ONSET

According to the International Association for Physicians in Aesthetic Medicine (IAPAM), the average onset of Dysport is just three hours. To put that number into perspective, BOTOX has an average onset of 72 hours, whereas Xeomin has an average onset of 96 hours. All four types of injections use BTX to force muscles to relax, but the formulation used in Dysport has the fastest onset at just three hours.

  • BOTOX takes about 5 to 7 days for results to appear, and lasts about 3 to 4 months

  • Dysport takes about 2 to 4 days for results to appear, and lasts about 4 months

  • Jeuveau takes about 3 to 5 days for results to appear, and lasts about 3 to 4 months

  • Xeomin takes about 5 to 7 days for results to appear, and lasts about 3 to 4 months

FDA APPROVAL

You can rest assured knowing that all four types of injections have been approved by the U.S. Food and Drug Administration (FDA). BOTOX was first approved by the FDA in 2002 to treat moderate to severe facial wrinkles. Dysport, on the other hand, received the FDA’s green light for glabellar, as well as cervical dystonia, in 2009. Just one year later, in 2010, the FDA approved Xeomin for the treatment of blepharospasm and cervical dystonia. Since then, the FDA has approved all four injections for many other cosmetic purposes.

STORAGE

It’s also worth mentioning that Xeomin is the only type of injection that can be stored at room temperature. BOTOX and Dysport both require refrigeration because they contain additives. In addition to BTX, BOTOX and Dysport contain compounds such as lactose, which is used to help spread BTX throughout the muscle tissue in which it’s injected. When stored at room temperature, commonly used additives like lactose may spoil. As a result, BOTOX and Dysport must be stored in a cool, refrigerated environment. Xeomin doesn’t contain any additives, however. In fact, it only contains incobotulinumtoxinA. And without any additives present, Xeomin can be safely stored at room temperature.

RESISTANCE

While rate, some people may develop a natural resistance to BOTOX, Dysport, Xeomin or Jeuveau. Over time, for example, these injections may become less effective due to the creation of antibodies. A person’s immune system may identify the ingredients used in these injections as being a foreign invader, so it responds by producing antibodies that neutralize their effect. While resistance can occur with any of these four types of injections, it’s most common with BOTOX and Dysport injections.

BOTOX and Dysport injections contain additives that can “irritate” the immune system and, thus, trigger the creation of antibodies. Xeomin, on the other hand, consists solely of BTX, so it’s less likely to cause resistance than its BOTOX and Dysport counterparts. The presence of additives in BOTOX and Dysport increases the risk of resistance. With that said, resistance to BTX is still rare with all three types of injections. Statistics show as few as one in 100 people who receive a BTX injection will develop a resistance to it. Nonetheless, rates of resistance are typically lower with Xeomin and Jeuveau.

INJECTION UNITS

Not all of these injections require the same amount of BTX (and filler ingredients for BOTOX and Dysport). According to the IAPAM, Dysport injections typically consist of 40 units per session. In comparison, Xeomin and BOTOX injections typically require just 20 units per session. Based on these figures, it takes about twice the amount of Dysport to achieve the same or similar results as BOTOX and Xeomin. But don’t let that fool you into thinking Dysport is more expensive BOTOX and Xeomin. The per-unit cost of Dysport is actually less, on average, than that of BOTOX and Xeomin. Surprisingly, Jeuveau requires the most units of all four injections. Each single-dose Jeuveau vial contains 100 units of botulinum toxin type A.

SESSIONS

If you’re planning to get BOTOX, Dysport, Xeomin or Jeuveau injections, you might be wondering what to expect. During a session, you’ll receive injections of the respective BTX formulation in your muscle tissue. If you’re suffering fro crow’s feet, for example, the injections will be into the skin around your eyes. Because they all contain BTX, all three formulations will force the muscle tissue around your eyes to relax, which should reduce or eliminate the appearance of crow’s feet.

Neither BOTOX, Dysport, Xeomin nor Jeuveau require sedation. BTX injections are a minimally invasive procedure that’s performed using a small, thin needle. As a result, sedation isn’t required. During a typical session, you may be asked to contract the muscles to improve the effectiveness of the injections. When you contract a muscle, the injection can be made directly into the tissue for maximum effectiveness. Once the BTX has been injected into a muscle, the muscle will begin to relax. BOTOX, Dysport, Xeomin and Jeuveau all contain BTX that, when injected into muscle tissue, temporarily blocks neurological signals.

It’s important to note that you won’t immediately see the full effects of BTX injections. Depending on the type of injection, it may take several weeks. The onset of the injections, however, are usually visible within three to 72 hours. Dysport has the fastest onset, whereas Xeomin has the slowest onset.

THE BOTTOM LINE

BOTOX, Dysport, Xeomin and Jeuveau are all injections involving BTX. The difference between them lies in their specific formulation of BTX. BOTOX uses onabotulinumtoxinA; Dysport uses abobotulinumtoxinA; Xeomin uses incobotulinumtoxinA; and Jeuveau uses botulinum toxin type A. All four of these formulations are still BTX, meaning they all block neurological signals. As previously explained, however, BOTOX, Dysport, Xeomin and Jeuveau have a few subtle nuances.

Want to learn more about BOTOX, Dysport, Xeomin and Jeuveau injections? Request a free consultation today!


DERMAL FILLERS

A facial filler includes a series of tiny injections which are applied at different depths within the skin’s surface..Creating a smoother and fuller appearance for the face. These fillers are made from absorbable material to adjust moderate to severe skin folds and facial wrinkles. This procedure is safe for individuals over the age of 21 years, however, the use of it is not limited to eliminating signs of aging, it can also be used to enhance facial structure.



What Types of Dermal Fillers Are Available?

There are natural dermal fillers and synthetic ones. Here is a quick comparison of some of the most popular derma fillers available on the market today: Restylane®, Juvederm®, Radiesse+® and Sculptra. Both Restylane and Juvederm offer custom formulations created for specific areas of the face.

Restylane®

Restylane was approved by the FDA in 2003 and the company has since added to their product line with their newest addition approved in 2020. It is made with hyaluronic acid (HA) – a substance that naturally exists in our skin. When hyaluronic acid is injected into specific areas, it restores the volume in that area.

Restylane is offered in different formulations, some including lidocaine, which helps ease injection discomfort. These formulations vary in particle size to address anything from fine lines and wrinkles to deep lines and also add increased volume.

The Restylane® product line includes:

  • Restylane®-l,

  • Restylane® Refyne,

  • Restylane® Silk,

  • Restylane® Kysse,

  • Restylane® Lyft,

  • Restylane® Defyne, and

  • Dysport.

Restylane can last anywhere from 6-9 months. Side effects can include bruising, swelling at the injection site, redness. Rare but other more serious side effects can include: infections, allergic reactions, keloids, and superficial necrosis, etc.

Radiesse®

Radiesse, which includes Radiesse+® and Belotero Balance®, are dermal fillers that contain calcium hydroxylapatite (CaHA), which is a long-lasting injectable drug that stimulates the production of collagen in your skin to improve your skin’s natural appearance. It can help to give you plump cheeks and full lips or make your hands appear less wrinkly.

Juvéderm®

The team at Genesis Medical also offer the line of dermal fillers from Juvéderm. Some of the fillers available include:

Juvéderm Ultra XC: to plump up your lips

Juvéderm Ultra Plus: thicker filler used to treat volume loss in your face, specifically around the mouth and nose

Juvéderm Voluma: to correct lost volume in your cheeks

Juvéderm Volbella®: adds volume to lips and smooths lines around your mouth

Juvéderm Vollure™ XC: smooths lines around the nose and mouth

Juvéderm is an HA dermal filler.

Genesis Medical also uses Sculptra®, which is a dermal filler that contains poly-L-lactic acid and is used to improve deep smile lines, and Bellafill®, which contains polymethylmethacrylate (PMMA) and can also improve your smile lines, as well as your recessed acne scars.

DERMAL FILLERS FOR MEN

Men also want to look younger and more athletic. Dermal fillers for men can help achieve that without surgery. A stronger jawline, more defined cheeks, and projected chin are the most popular requests from men when it comes to dermal fillers. Besides, dermal fillers work fantastically to make men look younger and fresher when applied to their faces. The results will be seen immediately and will last for up to two years.

WHAT IS THE COST OF DERMAL FILLERS AND INJECTABLES IN ONTARIO, CALIFORNIA?

The cost not only includes the price of the product, but more importantly, the skill and expertise of the specialist or healthcare professional who is administering your treatment. Enroll in our membership program to save money on treatments. Also, be sure to ask about our specials. We are in Ontario CA a central city our customers are usualy from Ontario, Rancho Cucamonga, Chino, Pomon, Claremont, Upland and Riverside and San Bernardino Counties